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Similar to neuronal nuclear inclusions, the axonal ATXN3 aggregates were ubiquitinated and immunopositive for the proteasome and autophagy-associated shuttle protein p62 [23, 30], strengthening the involvement of neuronal protein quality control (PQC) mechanisms in the management of this mutant protein

References Rothwell PM

GPX Activity (U/L) = (delta-OD S - delta-OD B ) / (Slope x 4 min) x 1000 x n, where n is the dilution factor

Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation

Macrophages facilitate resistance to Anti-VEGF therapy by altered VEGFR expression